ELISPOT assays and their diagnostic potential in Lyme disease and Lyme neuroborreliosis
نویسندگان
چکیده
منابع مشابه
Lyme neuroborreliosis: a diagnostic headache.
Case 1: A 4-year-old girl presented to our emergency department (ED) during the height of summer with 5 days of left-sided facial droop, which spared the forehead. The patient also complained of severe fatigue, 1 week of frontal headaches, urinary retention, intermittent erythematous rash around her eyes and behind her knees, and an increase in night terrors. Three days before admission, she wa...
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INTRODUCTION Descriptions of Lyme disease and dementia are rare. OBJECTIVE To describe patients with dementia and a positive "intrathecal anti-Borrelia antibody index" (AI), specific for neuroborreliosis. METHODS Among 1,594 patients seen for dementia, we prospectively identified and studied 20 patients (1.25%) with dementia and a positive AI. Patients underwent a battery of neuropsychologi...
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The aims of the present study were to assess the concentrations of different cytokines and chemokines in blood serum and cerebrospinal fluid (CSF) samples of patients with Lyme neuroborreliosis and to identify the possible marker(s) that would enable a distinction between clinically evident and suspected Lyme neuroborreliosis, as well as between Lyme neuroborreliosis and tick-borne encephalitis...
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James J. Nocton,* Bradley J. Bloom,* Barbara J. Rutledge, David H. Persing, Eric L. Logigian, Christopher H. Schmid, and Allen C. Steere Divisions of Rheumatology/Immunology, Pediatric Rheumatology, and Clinical Care Research, New England Medical Center and Floating Hospital for Children, Tufts University School ofMedicine, and Division ofNeurology, Brigham and Women's Hospital, Harvard Medical...
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The literature further states that, “Many healthcare practitioners mistakenly believe LD (Lyme disease) is not endemic to their state (in USA), causing them to omit the diagnosis from their differential or discount the patient’s concerns in this regard. Unfortunately, practitioners may not realize that LD has been found in every state. In states where B. burgdorferi carrying ticks are not highl...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2020
ISSN: 0009-9104,1365-2249
DOI: 10.1111/cei.13431